Dr Chiam Keng-Hwee
Bioinformatics Institute (BII), A*STAR
Research Interests: Bioinformatics, Computational Biology, Biophysics, Wound Healing in the Elderly
Keng Hwee’s group uses a combination of biophysical and bioinformatics tools to study cell migration. Cell migration is a critical process in every living organism, central to, for example, the morphogenesis of embryos, formation of tissues and organs, wound repair, as well as in less welcoming scenarios such as cancer metastasis. Some of their current projects include the study of amoeboid modes of cancer cell invasion, collective modes of epithelial cell sheet migration, and swimming and swarming modes of bacterial cell motility. He hopes that their approach will enable them to identify potential targets to perturb cell migration, which can eventually be translated into drugs to stop cancer cell invasion, promote wound and skin healing, or stop the aggregation of bacterial cells into biofilms.